澳门v泥斯

周小军


周小军,工学博士,澳门v泥斯讲师,硕士生导师。2016年毕业于东华大学。近年来承担国家自然科学基金青年基金项目、中国博士后科学基金面上项目,参与科技部、国家自然科学基金委等部门的科研项目,发表SCI论文30多篇,获得授权发明专利5项、实用新型2项。

 

主要研究方向

1. 功能化组织修复材料的设计及性能研究

2. 纳米材料的药物输送与诊疗研究

 

主持或参与的主要项目

1. 国家自然科学基金青年科学基金项目,双因子控制释放纳米纤维支架的仿生构建及骨再生机制研究,817021242018.01-2020.12,主持

2. 中国博士后科学基金面上资助,促血管化与成骨仿生骨支架的构建及其修复骨缺损的研究,2018M6304512018.05-2019.11,主持

3. 国家重点研发计划,血管化仿生关节多细胞精准3D打印技术与装备的开发及应用,2018YFB11056002018.05-2021.04,参与

4. 国家自然科学基金面上项目,Notch信号通路介导以Runx1 Ser48303424为靶点调控MSC成软骨分化成熟在骨关节炎软骨损伤修复中的作用及机制研究,817723262018.01-2021.12,参与

 

代表性学术论文

1. Zhou XJ, Liu PC, Nie W, Peng C, Li T, Qiang L, He CL*, Wang JW*. Incorporation of dexamethasone-loaded mesoporous silica nanoparticles into mineralized porous biocomposite scaffolds for improving osteogenic activity. Int. J. Biol. Macromol., 2020, 149: 116-126.

2. Zhou XJ, Zhang QQ, Chen L, Nie W, Wang WZ, Mo XM, He CL*. Versatile nanocarrier based on functionalized mesoporous silica nanoparticles to co-deliver osteogenic gene and drug for enhanced osteo-differentiation. ACS Biomater. Sci. Eng., 2019, 5(2): 710-723.

3. Han XG1, Zhou XJ1, Qiu KX, Feng W, Mo HM, Wang MQ, Wang JW*, He CL*. Strontium-incorporated mineralized PLLA nanofibrous membranes for promoting bone defect repair. Colloids Surf., B, 2019, 179: 363-373.

4. Li T, Ma HS, Ma HZ, Ma ZJ, Qiang L, Yang ZZ, Yang XX, Zhou XJ*, Dai KR*, Wang JW*. Mussel-inspired nanostructures potentiate the immunomodulatory properties and angiogenesis of mesenchymal stem cells. ACS Appl. Mater. Interfaces, 2019, 11(19): 17134-17146.

5. Liu ZL, Li T, Deng SN, Fu ST, Zhou XJ*, He Y*. Radiation induces apoptosis and osteogenic impairment through miR-22-mediated intracellular oxidative stress in bone marrow mesenchymal stem cells. Stem Cells Int., 2018, 2018: 5845402.

6.Li T, Liu ZL, Xiao M, Yang ZZ, Peng MZ, Li CD, Zhou XJ*, Wang JW*. Impact of bone marrow mesenchymal stem cell immunomodulation on the osteogenic effects of laponite. Stem Cell Res. Ther., 2018, 9(1): 100.

7. Zhou XJ, Wang WZ, Chen B, Feng W, Weng WZ, Zhang QQ, Nie W, Chen L, Mo XM, Su JC*, He CL*. Mesoporous silica nanoparticles/gelatin porous composite scaffolds with localized and sustained release of vancomycin for treatment of infected bone defects. J. Mater. Chem. B, 2018, 6(5): 740-752.

8. Li T, Liu ZL, Xiao M, Yang ZZ, Liu ZY, Zhou XJ*, Wang JW*. In vitro and in vivo studies of a gelatin/carboxymethyl chitosan/laponite® composite scaffold for bone tissue engineering. RSC Adv., 2017, 7(85): 54100-54110.

9. Zhou XJ, Chen L, Nie W, Wang WZ, Qin M, Mo XM, Wang HS, He CL*. Dual-responsive mesoporous silica nanoparticles mediated co-delivery of doxorubicin and bcl-2 siRNA for targeted treatment of breast cancer. J. Phys. Chem. C, 2016, 120(39): 22375-22387.

10. Zhou XJ, Feng W, Qiu KX, Chen L, Wang WZ, Nie W, Mo XM, He CL*. BMP-2 derived peptide and dexamethasone incorporated mesoporous silica nanoparticles for enhanced osteogenic differentiation of bone mesenchymal stem cells. ACS Appl. Mater. Interfaces. 2015; 7 (29): 15777-15789.

 

E-mail: zxj@dhu.edu.cn